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Invitrogen™ IL23R Polyclonal Antibody
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Catalog No. PIPA5113004
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100 μg
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Catalog No. Quantity
PIPA5113004 100 μg
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Catalog No. PIPA5113004 Supplier Invitrogen™ Supplier No. PA5113004
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Description

Rabbit Polyclonal Antibody

IL23R Polyclonal Antibody for Western Blot, ICC/IF, ELISA

IL-23R is a 629 aa, novel subunit of the receptor for cytokine IL23A/IL23 which pairs with the receptor molecule IL12RB1/IL12R beta 1and thus take part in IL23A signaling. Signal transduction analysis confirms that this protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. Alternative splicing results in six spliced isoforms of IL-23R. Reports suggest that IL-23R plays an important role in psoriasis pathogenesis and is also a potential therapeutic target in inflammatory bowel disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL23R
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Il23r
Gene Accession No. Q5VWK5
Gene Alias IBD17; IL 23R; IL-23 receptor; IL23R; IL-23R; interleukin 23 receptor; interleukin 23 receptor-like; interleukin-23 receptor
Gene Symbols Il23r
Host Species Rabbit
Immunogen Recombinant Human Interleukin-23 receptor protein (15-125AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 149233
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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