Invitrogen™ IL24 Monoclonal Antibody (303308)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA524013

Catalog No. PIMA524013

Description

No cross-reactivity with recombinant human IL-24 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.

Specifications

• Antigen: IL24
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q925S4
• Gene Symbols: IL24
• Immunogen: E. coli-derived recombinant mouse IL-24 Arg27-His181.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot, Immunocytochemistry
• Clone: 303308
• Conjugate: Unconjugated
• Gene: IL24
• Gene Alias: C49A; Cytokine-like protein Mob-5; FISP; IL 24; IL10B; Il24; IL-24; IL-4-induced secreted protein; Interleukin; interleukin 24; interleukin-24; Mda7; MDA-7; melanocyte-associated Mda-7; melanoma differentiation-associated gene 7 protein; Mob5; ST16; suppression of tumorigenicity 16 (melanoma differentiation); Suppression of tumorigenicity 16 protein; Th2-specific cytokine FISP
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 93672
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized