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Invitrogen™ IL24 Monoclonal Antibody (303308)
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Catalog No. PIMA524013
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100 μg
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Catalog No. Quantity
PIMA524013 100 μg
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Catalog No. PIMA524013 Supplier Invitrogen™ Supplier No. MA524013
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Description

Rat Monoclonal Antibody

No cross-reactivity with recombinant human IL-24 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL24
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 303308
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative; pH 7.4
Gene IL24
Gene Accession No. Q925S4
Gene Alias C49A; Cytokine-like protein Mob-5; FISP; IL 24; IL10B; Il24; IL-24; IL-4-induced secreted protein; Interleukin; interleukin 24; interleukin-24; Mda7; MDA-7; melanocyte-associated Mda-7; melanoma differentiation-associated gene 7 protein; Mob5; ST16; suppression of tumorigenicity 16 (melanoma differentiation); Suppression of tumorigenicity 16 protein; Th2-specific cytokine FISP
Gene Symbols IL24
Host Species Rat
Immunogen E. coli-derived recombinant mouse IL-24 Arg27-His181.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 93672
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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