IL24 Monoclonal Antibody (OTI5C8), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA809467

Catalog No. 50-168-2811

Description

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in maligt gliomas in a p53-independent manner.

Specifications

• Antigen: IL24
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q13007
• Gene Symbols: IL24
• Immunogen: Human recombit protein fragment corresponding to amino acids 52-206 of human IL24 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI5C8
• Conjugate: Unconjugated
• Gene: IL24
• Gene Alias: C49A, FISP, IL10B, MDA7, MOB5, ST16
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11009
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid