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IL24 Mouse anti-Human, Clone: OTI5C8, lyophilized, TrueMAB™
SDP

Catalog No. 501669514
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100 μg
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Catalog No. Quantity
50-166-9514 100 μg
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Catalog No. 50-166-9514 Supplier OriGene Supplier No. CF809467
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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in maligt gliomas in a p53-independent manner.

Specifications

Antigen IL24
Applications Western Blot
Classification Monoclonal
Clone OTI5C8
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene IL24
Gene Accession No. Q13007
Gene Alias C49A, FISP, IL10B, MDA7, MOB5, ST16
Gene Symbols IL24
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 52-206 of human IL24 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11009
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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