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Invitrogen™ IL24 Polyclonal Antibody
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Catalog No. 01676662
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100 μg
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Catalog No. Quantity
01-676-662 100 μg
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Catalog No. 01-676-662 Supplier Invitrogen™ Supplier No. PA141066
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Description

Rabbit Polyclonal Antibody

Suggested positive control: Jurkat, antigen standard for IL24 (transient overexpression lysate), Jurkat whole cell lysate. Immunogen sequence: KNYHNRTVEV RTLK.

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL24
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% gelatin and 0.05% sodium azide
Gene IL24
Gene Accession No. Q13007
Gene Alias C49A; Cytokine-like protein Mob-5; FISP; IL 24; IL10B; Il24; IL-24; IL-4-induced secreted protein; Interleukin; interleukin 24; interleukin-24; Mda7; MDA-7; melanocyte-associated Mda-7; melanoma differentiation-associated gene 7 protein; Mob5; ST16; suppression of tumorigenicity 16 (melanoma differentiation); Suppression of tumorigenicity 16 protein; Th2-specific cytokine FISP
Gene Symbols IL24
Host Species Rabbit
Immunogen Amino acids 123-136 of human IL-24.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11009
Target Species Human, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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