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IL24 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989748
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50-198-9748 100 μL
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Catalog No. 50-198-9748 Supplier Bioss Supplier No. BS10576R
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Description

Rabbit Polyclonal Antibody

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.

Specifications

Antigen IL24
Applications Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH
Gene IL24
Gene Accession No. Q13007
Gene Alias C49A; Cytokine-like protein Mob-5; FISP; IL 24; IL10B; IL24; IL-24; IL-4-induced secreted protein; interleukin 24; Interleukin-24; MDA7; MDA-7; melanocyte-associated Mda-7; Melanoma differentiation-associated gene 7 protein; Mob5; ST16; suppression of tumorigenicity 16 (melanoma differentiation); Suppression of tumorigenicity 16 protein; Th2-specific cytokine FISP
Gene Symbols IL24
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human IL24.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11009
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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