IL36 Beta/IL1F8 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 180431AP150UL

Catalog No. 50-173-1955

Description

IL-36B is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. IL-36B is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP. Like the related proteins IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown. The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells.

Specifications

• Antigen: IL36 Beta/IL1F8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IL36B
• Gene Alias: FIL1, FIL1 (ETA), FIL1 eta, FIL1H, IL 1 eta, IL 1F8, IL 1H2, IL1 ETA, IL1F8, IL1H2, Interleukin 1 eta, Interleukin 1 family member 8, Interleukin 1 homolog 2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27177
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.41 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q9NZH7
• Gene Symbols: IL36B
• Immunogen: IL36 Beta/IL1F8 Fusion Protein Ag12675
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG