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Invitrogen™ IL36B Polyclonal Antibody
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Catalog No. PIPA5100833
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100 μL
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PIPA5100833 100 μL
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Catalog No. PIPA5100833 Supplier Invitrogen™ Supplier No. PA5100833
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total IL1F8.

IL-36B is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. IL-36B is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP. Like the related proteins IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown. The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL36B
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene IL36B
Gene Accession No. Q9D6Z6, Q9NZH7
Gene Alias 2310043N20Rik; family of interleukin 1-eta; FIL1; FIL1 eta; FIL1-(ETA); Fil1e; FIL1H; FILI-(ETA); IL-1 eta; IL1-ETA; IL1F8; IL-1F8; IL1F8 (Canonical product IL-1F8a); IL-1F8 (FIL1-eta); IL1H2; IL-1H2; Il36b; Interleukin; interleukin 1 family, member 8; interleukin 1 family, member 8 (eta); interleukin 1, eta; interleukin 36, beta; interleukin-1 eta; Interleukin-1 family member 8; interleukin-1 homolog 2; Interleukin-1 Superfamily e; interleukin-36 beta
Gene Symbols Il1f8, IL36B
Host Species Rabbit
Immunogen A synthesized peptide derived from human IL36B(Accession Q9NZH7), corresponding to amino acid residues W126-M164.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27177, 69677
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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