Invitrogen™ IL4R Recombinant Rabbit Monoclonal Antibody (002), APC

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA546875

Catalog No. PIMA546875

Description

Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Rat IL4R (Met1-Arg232) and conjugated with APC under optimum conditions, the unreacted APC was removed. Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze!.

IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation. The IL4 response is involved in promoting Th2 differentiation. The secreted extracellular domain of IL4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. It has no signaling abilities. Allelic variations in the IL4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema.

Specifications

• Antigen: IL4R
• Classification: Recombinant Monoclonal
• Concentration: 100 μg/mL
• Formulation: PBS with 0.5% BSA and 0.03% Proclin 300
• Gene Accession No.: Q63257
• Gene Symbols: IL4R
• Immunogen: Recombinant protein encoding Rat IL4R (Met1-Arg232).
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry
• Clone: 002
• Conjugate: APC
• Gene: IL4R
• Gene Alias: 582J2.1; CD124; il-4 receptor; IL-4 receptor alpha chain; IL-4 receptor subunit alpha; IL-4-binding protein; IL4-BP; Il4r; IL4R nirs variant 1; IL-4R subunit alpha; IL4RA; IL-4RA; IL-4R-alpha; interleukin 4 receptor; interleukin 4 receptor, alpha; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha; Soluble IL-4 receptor subunit alpha; Soluble interleukin-4 receptor subunit alpha
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 25084
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov