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Invitrogen™ IL4R Recombinant Rabbit Monoclonal Antibody (209)
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Catalog No. PIMA535991
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100 μL
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PIMA535991 100 μL
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Catalog No. PIMA535991 Supplier Invitrogen™ Supplier No. MA535991
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Description

Rabbit Recombinant Monoclonal Antibody

IL4R Recombinant Monoclonal Antibody for Flow

IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation. The IL4 response is involved in promoting Th2 differentiation. The secreted extracellular domain of IL4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. It has no signaling abilities. Allelic variations in the IL4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL4R
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone 209
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene IL4R
Gene Accession No. P24394
Gene Alias 582J2.1; CD124; il-4 receptor; IL-4 receptor alpha chain; IL-4 receptor subunit alpha; IL-4-binding protein; IL4-BP; Il4r; IL4R nirs variant 1; IL-4R subunit alpha; IL4RA; IL-4RA; IL-4R-alpha; interleukin 4 receptor; interleukin 4 receptor, alpha; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha; Soluble IL-4 receptor subunit alpha; Soluble interleukin-4 receptor subunit alpha
Gene Symbols IL4R
Host Species Rabbit
Immunogen Recombinant Human IL-4R/CD124 Protein.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3566
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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