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Invitrogen™ IL4R Recombinant Rabbit Monoclonal Antibody (R001)
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Catalog No. PIMA543118
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200 μg
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PIMA543118 200 μg
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Catalog No. PIMA543118 Supplier Invitrogen™ Supplier No. MA543118
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Description

Rabbit Recombinant Monoclonal Antibody

Specificity: Human IL-4R/CD124.

IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation. The IL4 response is involved in promoting Th2 differentiation. The secreted extracellular domain of IL4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. It has no signaling abilities. Allelic variations in the IL4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL4R
Applications Neutralization
Classification Recombinant Monoclonal
Clone R001
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Arginine, histidine with 120mM NaCl, 0.02% Tween 80 and no preservative
Gene IL4R
Gene Accession No. P24394
Gene Alias 582J2.1; CD124; il-4 receptor; IL-4 receptor alpha chain; IL-4 receptor subunit alpha; IL-4-binding protein; IL4-BP; Il4r; IL4R nirs variant 1; IL-4R subunit alpha; IL4RA; IL-4RA; IL-4R-alpha; interleukin 4 receptor; interleukin 4 receptor, alpha; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha; Soluble IL-4 receptor subunit alpha; Soluble interleukin-4 receptor subunit alpha
Gene Symbols IL4R
Host Species Rabbit
Immunogen Recombinant Human IL-4R/CD124 Protein.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3566
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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