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Invitrogen™ IL9R alpha Monoclonal Antibody (AH9R7), PE
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Catalog No. PIMA528557
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Quantity:
100 Tests
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Catalog No. Quantity
PIMA528557 100 Tests
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Catalog No. PIMA528557 Supplier Invitrogen™ Supplier No. MA528557
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Description

Mouse Monoclonal Antibody

This antibody recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Recommended dilution is for 100 μL of whole blood or 1x10^6 cells in suspension.

The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL9R alpha
Applications Flow Cytometry
Classification Monoclonal
Clone AH9R7
Concentration 0.055 mg/mL
Conjugate PE
Formulation PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene IL9R
Gene Accession No. Q01113
Gene Alias CD129; IL-9 receptor; IL9R; IL-9R; interleukin 9 receptor; interleukin-9 receptor
Gene Symbols IL9R
Host Species Mouse
Immunogen Human CD129-transfected cell line.
Purification Method Size-exclusion chromatography
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3581
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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