Invitrogen™ IL9R alpha Monoclonal Antibody (AH9R7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA528556

Catalog No. PIMA528556

Description

This antibody recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Flow cytometry: It is recommended to use bright fluorochromes or signal multiplying detection; Functional Application: Blocking.

The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.

Specifications

• Antigen: IL9R alpha
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q01113
• Gene Symbols: IL9R
• Immunogen: Human CD129-transfected cell line.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: ELISA, Flow Cytometry, Functional Assay
• Clone: AH9R7
• Conjugate: Unconjugated
• Gene: IL9R
• Gene Alias: CD129; IL-9 receptor; IL9R; IL-9R; interleukin 9 receptor; interleukin-9 receptor
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3581
• Content And Storage: 4°C, do not freeze
• Form: Liquid