Invitrogen™ IL9R Monoclonal Antibody (33423.111)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA124800

Catalog No. PIMA124800

Description

The Neutralization Dose50 (ND50) for anti-human IL9R is approximately 2-4 μg/mL in the presence of 2 ng/mL of recombinant human IL9 using human MO7e cells. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Human Interleukin 9 (IL9) was first identified based on its proliferative activity on a human myeloid leukemic cell line. Human IL9 stimulates the proliferation of the human megakaryocytic leukemic cell line M07e. Human IL9 supports erythroid colony formation and synergizes with IL4 in the production of IgE and IgG. The interleukin 9 receptor is a member of the hematopoietin receptor superfamily. The cDNAs encoding mouse and human IL9 receptors have been isolated. The deduced mouse and human transmembrane proteins, sharing 53% amino acid sequence identity, contain 468 and 533 amino acid residues, respectively. A number of isoforms of IL9R, including a putative soluble form, have also been identified. The IL9 receptor is expressed in a variety of hematopoietic cells including T cells, neutrophils, mast cells, and macrophages.

Specifications

• Antigen: IL9R
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q01113
• Gene Symbols: IL9R
• Immunogen: Purified recombinant human soluble IL-9 receptor, expressed in Sf 21 insect cells.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Inhibition Assays, Neutralization, Western Blot
• Clone: 33423.111
• Conjugate: Unconjugated
• Gene: IL9R
• Gene Alias: CD129; IL-9 receptor; Il9r; IL-9R; interleukin 9 receptor; interleukin-9 receptor
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3581
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid