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Invitrogen™ ILK Monoclonal Antibody (3C7E1)
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Catalog No. PIMA549245
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100 μg
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Catalog No. Quantity
PIMA549245 100 μg
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Catalog No. PIMA549245 Supplier Invitrogen™ Supplier No. MA549245
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Description

Mouse Monoclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human MCF-7 whole cell, human Hela whole cell, human U87 whole cell, rat heart tissuerat kidney tissuemouse heart tissuemosue kidney tissue. IHC: human squamous cell lung carcinoma tissue, human spleen tissue, mouse kidney tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ILK
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 3C7E1
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene ILK
Gene Accession No. O55222, Q13418, Q99J82
Gene Alias 59 kDa serine/threonine-protein kinase; AA511515; epididymis secretory protein Li 28; ESTM24; HEL-S-28; ILK; ILK1; ILK-1; ILK2; ILK-2; integrin binding protein kinase; Integrin linked ILK; integrin linked kinase; integrin-linked kinase; integrin-linked kinase-2; integrin-linked protein kinase; loc; lost-contact; main squeeze; msq; P59; p59ILK; zgc:65842; zilk
Gene Symbols ILK
Host Species Mouse
Immunogen E.coli-derived human Integrin linked ILK recombinant protein (Position: M1-K452).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16202, 170922, 3611
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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