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Invitrogen™ ILK Polyclonal Antibody
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Catalog No. PIPA5119671
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100 μL
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PIPA5119671 100 μL
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Catalog No. PIPA5119671 Supplier Invitrogen™ Supplier No. PA5119671
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Description

Rabbit Polyclonal Antibody

Positive Control: Mouse skeletal muscle tissue, rat lung tissue, A431, MG-63, PANC-1, rat skeletal muscle tissue, human kidney tissue, human pancreas tissue, mouse heart tissue. Subcellular Location: Cell junction, Cell membrane, Cytoplasm.

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ILK
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene ILK
Gene Accession No. O55222, Q13418, Q99J82
Gene Alias 59 kDa serine/threonine-protein kinase; AA511515; epididymis secretory protein Li 28; ESTM24; HEL-S-28; ILK; ILK1; ILK-1; ILK2; ILK-2; integrin binding protein kinase; Integrin linked ILK; integrin linked kinase; integrin-linked kinase; integrin-linked kinase-2; integrin-linked protein kinase; loc; lost-contact; main squeeze; msq; P59; p59ILK; zgc:65842; zilk
Gene Symbols ILK
Host Species Rabbit
Immunogen Recombinant protein within Human Integrin linked ILK aa 1-290.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16202, 170922, 3611
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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