Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Indoles and derivatives
  7. iMAC2, Tocris Bioscience™

iMAC2, Tocris Bioscience™

Catalog No. 379410
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Suppressor of mitochondrial apoptosis

Inhibitor of mitochondrial apoptosis-induced channel (MAC) (IC50 = 28 nM). Reduces STS-induced apoptosis in FL5.12 cells by over 50%. Inhibits release of cytochrome c by Bid-induced Bax activation (IC50 = 0.68 μM).

Chemical Identifiers

CAS 335166-00-2
Molecular Formula C19H22Br2Cl2FN3
Molecular Weight (g/mol) 542.112
InChI Key JWCVUOLQOHIRML-UHFFFAOYSA-N
Synonym imac2, 3,6-dibromo-9-2-fluoro-3-1-piperazinyl propyl-9h-carbazole dihydrochloride, 3,6-dibromo-9-2-fluoro-3-piperazin-1-yl propyl carbazole dihydrochloride
PubChem CID 90488878
IUPAC Name 3,6-dibromo-9-(2-fluoro-3-piperazin-1-ylpropyl)carbazole;dihydrochloride
SMILES C1CN(CCN1)CC(CN2C3=C(C=C(C=C3)Br)C4=C2C=CC(=C4)Br)F.Cl.Cl

Specifications

Quantity 10 mg
Formula Weight 542.11
Percent Purity >98%
Chemical Name or Material iMAC2

Safety and Handling

Recommended Storage Desiccate at Room Temperature
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.