IMMY CrAg Lateral Flow Assay

Prescription-use laboratory assay aids in the diagnosis of crytococcosis

Manufacturer: IMMY CR2003

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Catalog No. 22-122-320

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Required Accessories : Pipetter (40 and 80μL); timer; disposable micro-centrifuge tubes, test tubes or microtiter plate

    Specifications

    Detectable Analytes Cryptococcal Antigen (CrAg) in Serum and CSF
    Includes LF specimen diluent 2.5mL, CrAg LF test strips 50, CrAg positive control 1mL, package insert
    Quantity 50 Tests
    Storage Requirements 22° to 25°C
    Test Time 10 min.
    Product Type Cryptococcus Antigen Assay Strips

    Immochromatographic test system for qualitative or semi-quantitative detection of capsular antigens of Cryptococcus species complex in serum and cerebral spinal fluid.

    • No specimen treatment needed
    • 10-Minute total test time
    • High sensitivity and specificity — twice as fast, and with greater sensitivity, compared to latex agglutination
    Dipstick sandwich immunochromatographic assay
    • Specimens and specimen diluent are added into a test tube or other reservoir
    • Lateral flow device is placed into the reservoir
    • Specimen wicking captures gold-conjugated, anti-CrAg monoclonal antibodies and gold-conjugated control antibodies deposited on test membrane
    • CrAg present in the specimen binds to the gold-conjugated, anti-CrAg antibodies
    • Antibody-antigen complex continues to wick up the membrane and interacts with test line containg immobilized anti-CrAg monoclonal antibodies
    • Gold-labeled antibody-antigen complex forms a sandwich at the test line causing a visible line to form
    • Positive test results create two lines (test and control)
    • Negative test results form only one line (control)
    • Failed test exists if a control line fails to develop

    Assay Kit Content

    • 6.5mL LF Specimen Diluent: Glycine-buffered saline containing blocking agents and a preservative
    • Pack of 50 CrAg LF Test Strips in desiccant vial
    • 1mL CrAg Positive Control: Glycine- buffered saline spiked with cryptococcal antigen (strain 184A – clinical isolate from Tulane University (Infection & Immunity, June 1983, p. 1052-1059))
    • Package insert

    For optimal results, sterile nonhemolyzed serum should be used.

  • Description & Specifications

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