IMPA1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-1042	Proteintech Group Inc 165931AP150UL	150 μL

Description

IMPA1, also known as Myo-inositol monophosphatase 1, is responsible for the procurement of inositol that is required for synthesis of phosphatidylinositol and polyphosphoinositides. IMPA1 exists as a homodimer and has been identified as the pharmacological target for lithium action in the brain. IMPA1 is the principal enzyme of the phosphatidyl inositol signaling pathway, and inhibition of inositol monophosphatase hydrolysis may underlie the anti-manic and anti-depressant actions of Li+. Studies indicate that a variation in the 277 codon coding region of the IMPA1 gene has not been observed in manic-depressive patients, therefore suggesting that polymorphisms or mutations in the noncoding regions of this gene may influence the lithium response in psychiatric patients.

Specifications

• Antigen: IMPA1
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: O55023, P29218, P97697
• Gene ID (Entrez): 3612, 55980, 83523
• Immunogen: IMPA1 Fusion Protein Ag9632
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: IMPA1

• Concentration: 0.21 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: IMP 1, IMPA, IMPA1, IMPase 1, Inositol monophosphatase 1
• Gene Symbols: IMPA1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody