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Invitrogen™ IMPDH1 Polyclonal Antibody
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Catalog No. PIPA5116702
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PIPA5116702 100 μL
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Catalog No. PIPA5116702 Supplier Invitrogen™ Supplier No. PA5116702
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Rabbit Polyclonal Antibody

Positive Samples: BT-474, HT-29, Mouse pancreas Immunogen sequence: MMGSLLAATT EAPGEYFFSD GVRLKKYRGM GSLDAMEKSS SSQKRYFSEG DKVKIAQGVS GSIQDKGSIQ KFVPYLIAGI QHGCQDIGAR SLSVLRSMMY SGELKFEKRT MSAQIEGGVH GLHSYEKRLY.

The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IMPDH1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene IMPDH1
Gene Accession No. D3ZLZ7, P20839, P50096
Gene Alias B930086D20Rik; DKFZp781N0678; HAMAP-Rule:MF_03156}; IMP (inosine 5'-monophosphate) dehydrogenase 1; IMP (inosine monophosphate) dehydrogenase 1; IMP dehydrogenase 1; IMP dehydrogenase 1 {ECO:0000255; IMPD; IMPD 1; IMPD 1 {ECO:0000255; IMPD1; IMPDH 1; IMPDH 1 {ECO:0000255; Impdh1; IMPDH-I; inosine 5'-phosphate dehydrogenase 1; inosine monophosphate dehydrogenase 1; inosine-5'-monophosphate dehydrogenase 1; inosine-5'-monophosphate dehydrogenase 1 {ECO:0000255; LCA11; RP10; sWSS2608
Gene Symbols IMPDH1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 434-563 of human IMPDH1 (NP_8990661).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23917, 3614, 362329
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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