Invitrogen™ IMPDH1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116702

Catalog No. PIPA5116702

Description

Positive Samples: BT-474, HT-29, Mouse pancreas Immunogen sequence: MMGSLLAATT EAPGEYFFSD GVRLKKYRGM GSLDAMEKSS SSQKRYFSEG DKVKIAQGVS GSIQDKGSIQ KFVPYLIAGI QHGCQDIGAR SLSVLRSMMY SGELKFEKRT MSAQIEGGVH GLHSYEKRLY.

The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: IMPDH1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IMPDH1
• Gene Alias: B930086D20Rik; DKFZp781N0678; HAMAP-Rule:MF_03156}; IMP (inosine 5'-monophosphate) dehydrogenase 1; IMP (inosine monophosphate) dehydrogenase 1; IMP dehydrogenase 1; IMP dehydrogenase 1 {ECO:0000255; IMPD; IMPD 1; IMPD 1 {ECO:0000255; IMPD1; IMPDH 1; IMPDH 1 {ECO:0000255; Impdh1; IMPDH-I; inosine 5'-phosphate dehydrogenase 1; inosine monophosphate dehydrogenase 1; inosine-5'-monophosphate dehydrogenase 1; inosine-5'-monophosphate dehydrogenase 1 {ECO:0000255; LCA11; RP10; sWSS2608
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23917, 3614, 362329
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.05 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: D3ZLZ7, P20839, P50096
• Gene Symbols: IMPDH1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 434-563 of human IMPDH1 (NP_8990661).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG