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Invitrogen™ IMPDH2 Recombinant Rabbit Monoclonal Antibody (4X3S10)
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Catalog No. PIMA535780
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100 μL
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PIMA535780 100 μL
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Catalog No. PIMA535780 Supplier Invitrogen™ Supplier No. MA535780
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: QANEVRKVKK YEQGFITDPV VLSPKDRVRD VFEAKARHGF CGIPITDTGR MGSRLVGIIS SRDIDFLKEE EHDCFLEEIM TKREDLVVAP AGITLKEANE ILQRSKKGKL PIVNEDDELV AIIARTDLKK NRDYPLASKD AKKQLLCGAA IGTHEDDKYR LDLLAQAGVD VVVLDSSQGN SIFQINMIKY IKDKYPNLQV I.

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IMPDH2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 4X3S10
Concentration 0.52 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene IMPDH2
Gene Accession No. E9PU28, P12268, P24547
Gene Alias HAMAP-Rule:MF_03156}; IMP (inosine 5'-monophosphate) dehydrogenase 2; IMP (inosine monophosphate) dehydrogenase 2; IMP dehydrogenase 2; IMP dehydrogenase 2 {ECO:0000255; IMP dehydrogenase type II; IMP oxireductase 2; IMPD; IMPD 2; IMPD 2 {ECO:0000255; IMPD2; IMPDH 2; IMPDH 2 {ECO:0000255; IMPDH II; Impdh2; IMPDH-II; inosine 5' phosphate dehydrogenase 2; inosine 5-monophosphate dehydrogenase 2; inosine 5'-phosphate dehydrogenase 2; inosine monophosphate dehydrogenase 2; inosine monophosphate dehydrogenase type II; inosine-5'-monophosphate dehydrogenase 2; inosine-5'-monophosphate dehydrogenase 2 {ECO:0000255
Gene Symbols IMPDH2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human IMPDH2 (P12268).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23918, 301005, 3615
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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