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Invitrogen™ IMPDH2 Polyclonal Antibody
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Catalog No. PIPA527494
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100 μL
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PIPA527494 100 μL
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Catalog No. PIPA527494 Supplier Invitrogen™ Supplier No. PA527494
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: H1299, mouse brain. Predicted reactivity: Mouse (97%), Rat (96%), Zebrafish (87%), Xenopus laevis (88%), Chicken (90%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IMPDH2
Applications Western Blot
Classification Polyclonal
Concentration 0.17 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene IMPDH2
Gene Accession No. E9PU28, P12268, P24547
Gene Alias HAMAP-Rule:MF_03156}; IMP (inosine 5'-monophosphate) dehydrogenase 2; IMP (inosine monophosphate) dehydrogenase 2; IMP dehydrogenase 2; IMP dehydrogenase 2 {ECO:0000255; IMP dehydrogenase type II; IMP oxireductase 2; IMPD; IMPD 2; IMPD 2 {ECO:0000255; IMPD2; IMPDH 2; IMPDH 2 {ECO:0000255; IMPDH II; Impdh2; IMPDH-II; inosine 5' phosphate dehydrogenase 2; inosine 5-monophosphate dehydrogenase 2; inosine 5'-phosphate dehydrogenase 2; inosine monophosphate dehydrogenase 2; inosine monophosphate dehydrogenase type II; inosine-5'-monophosphate dehydrogenase 2; inosine-5'-monophosphate dehydrogenase 2 {ECO:0000255
Gene Symbols IMPDH2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human IMPDH2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23918, 301005, 3615
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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