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Invitrogen™ IMPDH2 Polyclonal Antibody
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Catalog No. PIPA581938
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100 μL
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PIPA581938 100 μL
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Catalog No. PIPA581938 Supplier Invitrogen™ Supplier No. PA581938
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GFITDPVVLS PKDRVRDVFE AKARHGFCGI PITDTGRMGS RLVGIISSRD IDFLKEEEHD CFLEEIMTKR EDLVVAPAGI TLKEANEILQ RSKKGKLPIV NEDDELVAII ARTDLKKNRD YPLASKD Highest antigen sequence indentity to the following orthologs: Mouse - 98%, Rat - 98%.

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IMPDH2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene IMPDH2
Gene Accession No. P12268
Gene Alias HAMAP-Rule:MF_03156}; IMP (inosine 5'-monophosphate) dehydrogenase 2; IMP (inosine monophosphate) dehydrogenase 2; IMP dehydrogenase 2; IMP dehydrogenase 2 {ECO:0000255; IMP dehydrogenase type II; IMP oxireductase 2; IMPD; IMPD 2; IMPD 2 {ECO:0000255; IMPD2; IMPDH 2; IMPDH 2 {ECO:0000255; IMPDH II; Impdh2; IMPDH-II; inosine 5' phosphate dehydrogenase 2; inosine 5-monophosphate dehydrogenase 2; inosine 5'-phosphate dehydrogenase 2; inosine monophosphate dehydrogenase 2; inosine monophosphate dehydrogenase type II; inosine-5'-monophosphate dehydrogenase 2; inosine-5'-monophosphate dehydrogenase 2 {ECO:0000255
Gene Symbols IMPDH2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human IMPDH2. Recombinant protein control fragment (Product #RP-99364).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3615
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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