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Invitrogen™ IMPDH2 Recombinant Rabbit Monoclonal Antibody (JE40-87)
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Catalog No. PIMA534821
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100 μL
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PIMA534821 100 μL
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Catalog No. PIMA534821 Supplier Invitrogen™ Supplier No. MA534821
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Rabbit Recombinant Monoclonal Antibody

Positive Control: Daudi, A431, LOVO, PC-3M, rat kidney tissue, human tonsil tissue, human thyroid gland tissue, mouse testis tissue.

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IMPDH2
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JE40-87
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene IMPDH2
Gene Accession No. P12268
Gene Alias HAMAP-Rule:MF_03156}; IMP (inosine 5'-monophosphate) dehydrogenase 2; IMP (inosine monophosphate) dehydrogenase 2; IMP dehydrogenase 2; IMP dehydrogenase 2 {ECO:0000255; IMP dehydrogenase type II; IMP oxireductase 2; IMPD; IMPD 2; IMPD 2 {ECO:0000255; IMPD2; IMPDH 2; IMPDH 2 {ECO:0000255; IMPDH II; Impdh2; IMPDH-II; inosine 5' phosphate dehydrogenase 2; inosine 5-monophosphate dehydrogenase 2; inosine 5'-phosphate dehydrogenase 2; inosine monophosphate dehydrogenase 2; inosine monophosphate dehydrogenase type II; inosine-5'-monophosphate dehydrogenase 2; inosine-5'-monophosphate dehydrogenase 2 {ECO:0000255
Gene Symbols IMPDH2
Host Species Rabbit
Immunogen Recombinant protein within Human IMPDH2 aa 80-320.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3615
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
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