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Invitrogen™ Importin 4 Polyclonal Antibody
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Catalog No. PIPA5100069
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100 μL
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PIPA5100069 100 μL
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Catalog No. PIPA5100069 Supplier Invitrogen™ Supplier No. PA5100069
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total IPO4.

Importin-4 is a protein that in humans is encoded by the IPO4 gene. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Importin 4
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Ipo4
Gene Accession No. Q8TEX9, Q8VI75
Gene Alias 8430408O15Rik; AA409693; Imp4; Imp4a; IMP4B; importin 4; importin 4a; importin-4; Importin-4a; importin-4b; IPO4; Ran-binding protein 4; ranBP4
Gene Symbols Ipo4
Host Species Rabbit
Immunogen A synthesized peptide derived from human IPO4(Accession Q8TEX9), corresponding to amino acid residues L440-N490.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 290228, 75751, 79711
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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