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Invitrogen™ Importin 4 Polyclonal Antibody
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Catalog No. PA550433
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100 μL
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PA550433 100 μL
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Catalog No. PA550433 Supplier Invitrogen™ Supplier No. PA550433
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total IPO4 protein.

Importin-4 is a protein that in humans is encoded by the IPO4 gene. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Importin 4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 2.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Ipo4
Gene Accession No. Q8TEX9
Gene Alias 8430408O15Rik; AA409693; Imp4; Imp4a; IMP4B; importin 4; importin 4a; importin-4; Importin-4a; importin-4b; IPO4; Ran-binding protein 4; ranBP4
Gene Symbols Ipo4
Host Species Rabbit
Immunogen Fusion protein corresponding to residues near the C terminal of human importin 4.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79711
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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