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Invitrogen™ Importin 4 Polyclonal Antibody
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Catalog No. PIPA558634
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100 μL
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PIPA558634 100 μL
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Catalog No. PIPA558634 Supplier Invitrogen™ Supplier No. PA558634
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AFLPYMESVF EEVFKLLECP HLNVRKAAHE ALGQFCCALH KACQSCPSEP NTAALQAALA RVVPSYMQAV NRERERQVVM AVLE Highest antigen sequence identity to the following orthologs: Mouse - 69%, Rat - 77%.

Importin-4 is a protein that in humans is encoded by the IPO4 gene. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Importin 4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Ipo4
Gene Accession No. Q8TEX9
Gene Alias 8430408O15Rik; AA409693; Imp4; Imp4a; IMP4B; importin 4; importin 4a; importin-4; Importin-4a; importin-4b; IPO4; Ran-binding protein 4; ranBP4
Gene Symbols Ipo4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Importin 4. Recombinant protein control fragment (Product #RP-97613).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79711
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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