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Invitrogen™ Importin 7 Polyclonal Antibody
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Catalog No. PIPA523464
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100 μg
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Catalog No. Quantity
PIPA523464 100 μg
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Catalog No. PIPA523464 Supplier Invitrogen™ Supplier No. PA523464
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Description

Rabbit Polyclonal Antibody

The amino acid sequence used as immunogen is 88% homologous in Xenopus.

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of RaNULLs GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Importin 7
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide
Gene Ipo7
Gene Accession No. O95373, Q9EPL8
Gene Alias A330055O14Rik; C330016G14; FLJ14581; Imp7; importin 7; importin-7; IPO7; MGC138673; RAN binding protein 7; RAN-binding protein 7; RanBP7
Gene Symbols Ipo7
Host Species Rabbit
Immunogen A portion of amino acids 1-76 of human IOP7.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10527, 233726, 308939
Target Species Human, Mouse, Rat, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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