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Invitrogen™ Importin 8 Polyclonal Antibody
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Catalog No. PIPA553801
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100 μL
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PIPA553801 100 μL
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Catalog No. PIPA553801 Supplier Invitrogen™ Supplier No. PA553801
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LLLHTLERIQ LPHNPGPITV QFINQWMNDT DCFLGHHDRK MCIIGLSILL ELQNRPPAVD AVVGQIVPSI LFLFLGLKQV CATRQLVNRE DRSKAEKADM EENE Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 87%.

Importin 8 is a 1037 amino acidnuclear protein with a RAN binding site. It belongs to RAN-binding protein super family and hence shares an N-terminal sequence motif with importin-beta that appears to account for RAN GTP binding. It binds to the nuclear pore complex (NPC) and is well known as a transport carrier that mediates nuclear import of ribosomal proteins with a classical nuclear localization signal. Importin 8 works by binding to the nuclear pore complex and, along with RANGTP and RANBP1, inhibits the GAP stimulation of the RAN GTPase. Along with transportin it also helps in the nuclear import of SRP19.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Importin 8
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration Lot-Specific
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene IPO8
Gene Accession No. O15397
Gene Alias 6230418K12Rik; Abcc10; ATP-binding cassette, sub-family C (CFTR/MRP), member 10; C130009K11Rik; FLJ26580; imp8; importin 8; importin-8; IPO8; MRP7; Om1; OM-1; oocyte maturation 1; RAN binding protein 8; ran-binding protein 8; RANBP8
Gene Symbols IPO8
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Importin 8. Recombinant protein control fragment (Product #RP-91846).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10526
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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