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Importin beta Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Encompass_Preferred

$395.30

Specifications

Antigen Importin beta
Concentration 0.15 mg/mL
Applications Immunohistochemistry (Paraffin), Western Blot
Conjugate Unconjugated
Format Liquid
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-172-6004
Encompass_Preferred
View Documents Promotion Details
Proteintech Group IncSupplier Diversity Partner
100771AP150UL
150 μL
Each for $395.30
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Description

Description

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
Specifications

Specifications

Importin beta
Immunohistochemistry (Paraffin), Western Blot
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Polyclonal
-20°C
0.15 mg/mL
Unconjugated
Rabbit
Human, Mouse, Rat
IgG
Antigen Affinity Chromatography
Antibody
SDS
Product Certifications
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