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Tocris Bioscience™ INCA-6
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Catalog No. 216210R
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Catalog No. Quantity
21-621-0R 10 mg
21-625-0 50 mg
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Catalog No. 21-621-0R Supplier Tocris Bioscience™ Supplier No. 2162/10
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Description

Inhibitor of calcineurin-substrate association

INCA-6 is an inhibitor of interaction between calcineurin and its substrate nuclear factor of activated T cells (NFAT); blocks at the substrate recognition site but not at the catalytic site (Kd = 0.8 mM). Inhibits NFAT dephosphorylation and nuclear import. Also prevents induction of cytokine mRNAs that are downstream targets of NFAT.

Specifications

Quantity 10 mg
Product Type INCA-6
Purity >98%
Molecular Weight (g/mol) 284.31
Inhibitors INCA-6

For Research Use Only

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