Invitrogen™ INCA1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560689

Catalog No. PIPA560689

Description

Immunogen sequence: KKRRPCLEGM QQQGLGGVPA RVRAVTYHLE DLRRRQSIIN ELKKAQWGSS GAASEPVVLG EEGCGFPSTN EYPD Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 68%.

Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor (PubMed:21540187). Inhibits cell growth and cell proliferation and may play a role in cell cycle control. Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth. [UniProt].

Specifications

• Antigen: INCA1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INCA1
• Gene Alias: AI842396; HSD45; INCA1; Inhibitor of CDK interacting with cyclin A1; inhibitor of CDK, cyclin A1 interacting protein 1; protein INCA1; RGD1306656
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 388324
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q0VD86
• Gene Symbols: INCA1
• Immunogen: Recombinant protein corresponding to Human INCA1. Recombinant protein control fragment (Product #RP-93541).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG