INCENP Monoclonal Antibody (58-217-2), Active Motif™

Catalog No.	Quantity
50-199-2673	200 μg
50-199-2674	10 μg

Catalog No. 50-199-2673 Supplier Active Motif Supplier No. 39259

Description

Mouse Monoclonal Antibody

Chromosomal passenger proteins are members of a group of proteins that move from centromeres to the spindle midzone during mitosis. INCENP (Inner Centromere Protein) is a chromosomal passenger protein with an essential role in mitosis and meiosis. It is a complex highly basic multidomain protein that is dynamically translocated from metaphase chromosomes to the spindle midzone during or just prior to anaphase. Some INCENP transfers to the equatorial cortex before formation of the cleavage furrow. Ultimately, it is discarded in the midbody at the completion of cytokinesis.

Specifications

• Antigen: INCENP
• Applications: Immunocytochemistry, Immunofluorescence
• Classification: Monoclonal
• Clone: 58-217-2
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
• Gene: Incenp
• Gene Accession No.: Q9NQS7, Q9WU62
• Gene Alias: 2700067E22Rik; AU019509; binds and activates aurora-B and -C in vivo and in vitro; C130081E20; C77457; chromosomal passenger protein; Incenp; Inner centromere protein; inner centromere protein antigens 135/155kDa; inner centromere protein INCENP
• Gene Symbols: Incenp
• Host Species: Mouse
• Immunogen: This INCENP antibody was raised against a recombinant protein corresponding to amino acid residues 231-398 of human INCENP.
• Purification Method: Protein A
• Quantity: 200 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 16319, 3619
• Target Species: Human, Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1