Invitrogen™ INCENP Monoclonal Antibody (58-217)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ 392800

Catalog No. 39-280-0

Description

INCENP Monoclonal Antibody for Western Blot, ICC/IF, IP, ELISA

Chromosomal passenger proteins are members of a group of proteins that move from centromeres to the spindle midzone during mitosis. INCENP (Inner Centromere Protein) is a chromosomal passenger protein with an essential role in mitosis and meiosis. It is a complex highly basic multidomain protein that is dynamically translocated from metaphase chromosomes to the spindle midzone during or just prior to anaphase. Some INCENP transfers to the equatorial cortex before formation of the cleavage furrow. Ultimately, it is discarded in the midbody at the completion of cytokinesis.

Specifications

• Antigen: INCENP
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.1% sodium azide; pH 7.4
• Gene Accession No.: Q9NQS7
• Gene Symbols: Incenp
• Immunogen: Recombinant human INCENP (inner centromere protein).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 58-217
• Conjugate: Unconjugated
• Gene: Incenp
• Gene Alias: 2700067E22Rik; AU019509; binds and activates aurora-B and -C in vivo and in vitro; C130081E20; C77457; chromosomal passenger protein; Incenp; Inner centromere protein; inner centromere protein antigens 135/155kDa; inner centromere protein INCENP
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3619
• Content And Storage: -20°C
• Form: Liquid