Invitrogen™ INCENP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA584843

Catalog No. PIPA584843

Description

Immunogen sequence: IICHSYLERL LNVEVPQKVG SEQKEPPEEA EPVAAAEPEV PENNGNNSWP HNDTEIANST PNPKPAASSP ETPSAGQQEA KTDQADGP.

Chromosomal passenger proteins are members of a group of proteins that move from centromeres to the spindle midzone during mitosis. INCENP (Inner Centromere Protein) is a chromosomal passenger protein with an essential role in mitosis and meiosis. It is a complex highly basic multidomain protein that is dynamically translocated from metaphase chromosomes to the spindle midzone during or just prior to anaphase. Some INCENP transfers to the equatorial cortex before formation of the cleavage furrow. Ultimately, it is discarded in the midbody at the completion of cytokinesis.

Specifications

• Antigen: INCENP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Incenp
• Gene Alias: 2700067E22Rik; AU019509; binds and activates aurora-B and -C in vivo and in vitro; C130081E20; C77457; chromosomal passenger protein; Incenp; Inner centromere protein; inner centromere protein antigens 135/155kDa; inner centromere protein INCENP
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3619
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NQS7
• Gene Symbols: Incenp
• Immunogen: Recombinant protein corresponding to Human INCENP. Recombinant protein control fragment (Product #RP-107754).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG