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Invitrogen™ INCENP Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA587463
Description
Immunogen sequence: ALNVTVDVQS PACTSYQMTP QGHRAPPKIN PDNYGMDLNS DDSTDDEAHP RKPIPTWARG TPLSQAIIHQ YYHPPNLLEL FGTILPLDLE DIFKKSKPRY HKRTSSAVWN SPPLQGARVP SSLAYSLKKH; Positive Samples: HeLa, Jurkat, Rat thymus; Cellular Location: Chromosome, Cytoplasm, Nucleus, centromere, cytoskeleton, kinetochore, spindle.
Chromosomal passenger proteins are members of a group of proteins that move from centromeres to the spindle midzone during mitosis. INCENP (Inner Centromere Protein) is a chromosomal passenger protein with an essential role in mitosis and meiosis. It is a complex highly basic multidomain protein that is dynamically translocated from metaphase chromosomes to the spindle midzone during or just prior to anaphase. Some INCENP transfers to the equatorial cortex before formation of the cleavage furrow. Ultimately, it is discarded in the midbody at the completion of cytokinesis.
Specifications
INCENP | |
Polyclonal | |
Unconjugated | |
Incenp | |
2700067E22Rik; AU019509; binds and activates aurora-B and -C in vivo and in vitro; C130081E20; C77457; chromosomal passenger protein; Incenp; Inner centromere protein; inner centromere protein antigens 135/155kDa; inner centromere protein INCENP | |
Rabbit | |
Affinity Chromatography | |
RUO | |
293733, 3619 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot | |
1.21 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q9NQS7 | |
Incenp | |
Recombinant fusion protein containing a sequence corresponding to amino acids 785-914 of human INCENP (NP_0646232). | |
100 μL | |
Primary | |
Human, Rat | |
Antibody | |
IgG |
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