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Invitrogen™ INCENP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587463

Catalog No. PIPA587463


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Description

Description

Immunogen sequence: ALNVTVDVQS PACTSYQMTP QGHRAPPKIN PDNYGMDLNS DDSTDDEAHP RKPIPTWARG TPLSQAIIHQ YYHPPNLLEL FGTILPLDLE DIFKKSKPRY HKRTSSAVWN SPPLQGARVP SSLAYSLKKH; Positive Samples: HeLa, Jurkat, Rat thymus; Cellular Location: Chromosome, Cytoplasm, Nucleus, centromere, cytoskeleton, kinetochore, spindle.

Chromosomal passenger proteins are members of a group of proteins that move from centromeres to the spindle midzone during mitosis. INCENP (Inner Centromere Protein) is a chromosomal passenger protein with an essential role in mitosis and meiosis. It is a complex highly basic multidomain protein that is dynamically translocated from metaphase chromosomes to the spindle midzone during or just prior to anaphase. Some INCENP transfers to the equatorial cortex before formation of the cleavage furrow. Ultimately, it is discarded in the midbody at the completion of cytokinesis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

INCENP
Polyclonal
Unconjugated
Incenp
2700067E22Rik; AU019509; binds and activates aurora-B and -C in vivo and in vitro; C130081E20; C77457; chromosomal passenger protein; Incenp; Inner centromere protein; inner centromere protein antigens 135/155kDa; inner centromere protein INCENP
Rabbit
Affinity Chromatography
RUO
293733, 3619
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot
1.21 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9NQS7
Incenp
Recombinant fusion protein containing a sequence corresponding to amino acids 785-914 of human INCENP (NP_0646232).
100 μL
Primary
Human, Rat
Antibody
IgG
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