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  5. Tocris Bioscience™ IND 1316

Tocris Bioscience™ IND 1316
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Catalog No. 768510
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

AMPK activator

IND 1316 is an activator of AMP-activated protein kinase (AMPK). In vitro, it activates AMPK in a dose-dependent manner and induces different MAPK pathways (p38 and JNK). In vivo, it reduces the neuropathological symptoms in two animal models of Huntington's Disease (nematodes and mice). It shows very low toxicity even at high concentrations (>200 μM). This compound is orally bioavailable.

Specifications

Chemical Name or Material 3-[3-(Phenylmethoxy)phenyl]-1 H-indole-2-carboxylic acid
CAS 1888473-12-8
Quantity 10 mg
Target AMPK Activators
Molecular Formula C22H17NO3
Purity 0.98
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