Indole-2-carboxylic acid, 98+%

Description

CAS: 1477-50-5 | C9H7NO2 | 161.16 g/mol

Reactant for total synthesis of (±)-dibromophakellin and analogs, synthesis of the pyrrolizidine alkaloid (±)-trachelanthamidine, stereo selective preparation of renieramycin G analogs, preparation of spirooxoindolepyrrolidines via reduction of indole-2-carboxylic acid followed by oxidation, condensation, reduction, amidation and Kharasch radical cyclization, Pd-catalyzed cyclization and N,N-(pentane)diylbis[indolecarboxamide] and N,N-[phenylenebis(methylene)]bis[indolecarboxamide] derivatives.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Reactant for total synthesis of (±)-dibromophakellin and analogs, synthesis of the pyrrolizidine alkaloid (±)-trachelanthamidine, stereo selective preparation of renieramycin G analogs, preparation of spirooxoindolepyrrolidines via reduction of indole-2-carboxylic acid followed by oxidation, condensation, reduction, amidation and Kharasch radical cyclization, Pd-catalyzed cyclization and N,N′-(pentane)diylbis[indolecarboxamide] and N,N′-[phenylenebis(methylene)]bis[indolecarboxamide] derivatives.

Solubility
Soluble in clear yellow solution 5% in ethanol, dimethyl sulfoxide and methanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Specifications

Chemical Identifiers

• CAS: 1477-50-5
• Molecular Formula: C9H7NO2
• Molecular Weight (g/mol): 161.16
• MDL Number: MFCD00005611
• InChI Key: HCUARRIEZVDMPT-UHFFFAOYSA-N
• Synonym: indole-2-carboxylic acid, 2-carboxyindole, 2-indolecarboxylic acid, indol-2-carboxylic acid, 1h-indolecarboxylic acid, indole-2-carboxylate, 2-indolylformic acid, 2-indole carboxylic acid, 1h-indol-2-carbons, carboxyindole
• PubChem CID: 72899
• IUPAC Name: 1H-indole-2-carboxylic acid
• SMILES: OC(=O)C1=CC2=CC=CC=C2N1

• Melting Point: ∼205°C (decomposition)
• Quantity: 10 g
• Beilstein: 124132
• Solubility Information: Soluble in clear yellow solution 5% in ethanol,dimethyl sulfoxide and methanol.
• Formula Weight: 161.16
• Percent Purity: ≥98%
• Chemical Name or Material: Indole-2-carboxylic acid

Safety and Handling

Hazard Category	H302+H312-H315-H319-H335
Hazard Statement	GHS H Statement H301-H311-H315-H319-H335 Toxic if swallowed. Toxic in contact with skin. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
EINECSNumber	216-030-4
RTECSNumber	NK7882812
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only