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R&D Systems™ INDY
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Catalog No. 499710R Shop All Novus Products
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Catalog No. Quantity
49-971-0R 10 mg
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Catalog No. 49-971-0R Supplier R&D Systems™ Supplier No. 4997/10

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Description

A Tocris product, part of R&D Systems. DYRK1A/B inhibitor

INDY is a DYRK1A/B inhibitor (IC50 values are 0.23 and 0.24 μM, for DYRK1B and DYRKA respectively). Binds at the ATP-binding cleft of the enzyme. Reverses aberrant tau-phosphorylation and rescues repressed calcineurin/NFAT signaling. Impairs the self-renewal capacity of subventricular zone neural stem cells. Also available as a prodrug, proINDY (Cat. No. 4998).

Specifications

Quantity 10 mg
Product Line Tocris
Product Type INDY
Purity >98%
Molecular Weight (g/mol) 235.3
Inhibitors INDY

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