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Tocris Bioscience™ INF 4E
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Catalog No. 617210
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61-721-0 10mg
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Inflammasomes Inhibitors

INF 4E is a NLRP3 inflammasome and caspase-1 inhibitor (Ki = 9.6 μM for caspase-1). Inhibits Nigericin (Cat. No. 4312) or ATP (Cat.No. 3245) induced pyroptosis of PMA-differentiated and LPS-primed THP-1 cells and activates the Keap1-Nrf2 pathway.

Specifications

Chemical Name or Material Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate
CAS 88039-46-7
Assay Percent Range >98%
Quantity 10 mg
Molecular Formula C12H13ClO3
Formula Weight Observed MW: 240.68
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