Invitrogen™ Influenza A H1N1 Polyclonal Antibody

Catalog No.	Quantity
PA17221	1 mL

Catalog No. PA17221 Supplier Invitrogen™ Supplier No. PA17221

Description

Goat Polyclonal Antibody

PA1-7221 detects the influenza A virus (H1N1). This antibody does not react with influenza B, RSV, Parainfluenza 1-3 or Adenovirus, but may ract with chicken cellular proteins. PA1-7221 has been successfully used in immunofluorescence, ELISA, western blotting and immunohistochemistry procedures. The PA1-7221 immunogen is influenza A, strain USSR (H1N1). PA1-7221 may be used in place of neat antiserum in almost any appropiate antibody-based technique. It is also suitable for conjugation purposes.

Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States. The virus spread quickly around the world and on June 11, 2009, the World Health Organization declared it a pandemic. Influenza A virus has one of sixteen possible Hemagglutinin (HA) surface proteins and one of nine possible Neuraminidase (NA) surface proteins. The Hemagglutinin protein facilitates viral attachment while Neuraminidase is involved in viral release. These proteins also elicit immune responses that prevent infection or independently reduce viral replication. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. The distinct antigenic properties of the new swine influenza virus compared with seasonal influenza A (H1N1) virus suggest that human immunity against new swine influenza virus is limited, although the age distribution of reported cases suggests some degree of protection in older age groups.

Specifications

• Antigen: Influenza A H1N1
• Applications: ELISA, Western Blot, Western Blot
• Classification: Polyclonal
• Concentration: 5.0 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% sodium azide; pH 7.2
• Gene Alias: H1N1; Influenza H1N1
• Host Species: Goat
• Immunogen: Influenza A, strain USSR (H1N1).
• Purification Method: IgG fraction
• Quantity: 1 mL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Virus
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG