Invitrogen™ Influenza A virus Nucleoprotein Recombinant Rabbit Monoclonal Antibody (HL1321)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA550311

Catalog No. FEMA550311

Description

This antibody is specific for Influenza A virus Nucleoprotein protein (H1N1, H3N2, H5N8, and H10N3), and it does not cross-react with Influenza B virus Nucleoprotein protein.

The nucleoprotein (NP) of Influenza A virus encapsidates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56 (Portela et al 2002).

Specifications

• Antigen: Influenza A virus Nucleoprotein
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with no preservative
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: HL1321
• Conjugate: Unconjugated
• Gene Alias: Influenza nucleoprotein
• Immunogen: Recombinant fragment corresponding to C-terminal region of Influenza A virus H5N8 Nucleoprotein (A/Astrakhan/3212/2020)). The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid