Influenza A virus Matrix Protein 2 Rabbit anti-Virus, Polyclonal, Bioss

Catalog No.	Quantity
50-198-0225	100 μL

Catalog No. 50-198-0225 Supplier Bioss Supplier No. BS0344R

Description

Rabbit Polyclonal Antibody

Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur. Also plays a role in viral proteins secretory pathway. Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.

Specifications

• Antigen: Influenza A virus Matrix Protein 2
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from Influenza A virus H5N1 Matrix Protein-2 .
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Virus
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG