Invitrogen™ ING1 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547772

Catalog No. PIPA547772

Description

In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) ING2 and less than 1% cross-reactivity with with rhING3, rhING4, and rhING5 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Specifications

• Antigen: ING1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ING1
• Gene Alias: 2610028J21Rik; AA407184; AI875420; growth inhibitor ING1; growth inhibitory protein ING1; ING1; inhibitor of growth family member 1; inhibitor of growth family, member 1; inhibitor of growth protein 1; mING1h; p24ING1c; p33; p33ING; p33ING1; p33ING1b; p33ING1c; p37Ing1b; p47; p47ING1a; tumor suppressor ING1
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3621
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q9UK53
• Gene Symbols: ING1
• Immunogen: E. coli-derived recombinant human ING1 Met213-Ser327.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG