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Invitrogen™ ING3 Polyclonal Antibody
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Catalog No. PIPA527717
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100 μL
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PIPA527717 100 μL
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Catalog No. PIPA527717 Supplier Invitrogen™ Supplier No. PA527717
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: H1299, HepG2. Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ING3
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene ING3
Gene Accession No. Q9NXR8
Gene Alias 1300013A07Rik; Eaf 4; Eaf4; FLJ20089; HSPC301; ING 2; ING 3; ING2; ING3; ing3 protein; inhibitor of growth family member 3; inhibitor of growth family, member 3; inhibitor of growth protein 3; inhibitor of growth protein 3-like protein; MEAF4; p47 p47 ING3; p47 regulator protein; p47ING3; p47ING3 protein; zgc:56327
Gene Symbols ING3
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ING3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54556
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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