ING3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-0778	150 μL

Catalog No. 50-173-0778 Supplier Proteintech Group Inc Supplier No. 161871AP150UL

Description

Rabbit Polyclonal Antibody

This antibody is specifically against p47ING3.

The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.

Specifications

• Antigen: ING3
• Applications: Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.14 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: ING3
• Gene Accession No.: Q498T3, Q8VEK6, Q9NXR8
• Gene Alias: Eaf4, ING2, ING3, Inhibitor of growth protein 3, p47ING3
• Gene Symbols: Ing3
• Host Species: Rabbit
• Immunogen: Peptide
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 312154, 54556, 71777
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG