INHA Monoclonal Antibody (C1), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA543728

Catalog No. PIMA543728

Description

The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.

Specifications

• Antigen: INHA
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: P05111
• Gene Symbols: INHA
• Immunogen: Ala25-Cys363 (Accession P05111), with N-terminal His Tag
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: C1
• Conjugate: Unconjugated
• Gene: INHA
• Gene Alias: A inhibin subunit; A-inhibin subunit; AW555078; IHA; Inha; inhibin; inhibin alpha; inhibin alpha chain; inhibin alpha subunit
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 3623
• Content And Storage: -20°C
• Form: Liquid