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Invitrogen™ INHA Polyclonal Antibody
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Catalog No. PIPA529231
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100 μL
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PIPA529231 100 μL
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Catalog No. PIPA529231 Supplier Invitrogen™ Supplier No. PA529231
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Molt-4. Predicted reactivity: Rat (80%), Pig (85%), Rabbit (82%), Sheep (82%), Rhesus Monkey (97%), Bovine (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
TRUSTED_SUSTAINABILITY

Specifications

Antigen INHA
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.27 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene INHA
Gene Accession No. P05111, Q04997
Gene Alias A inhibin subunit; A-inhibin subunit; AW555078; IHA; Inha; inhibin; inhibin alpha; inhibin alpha chain; inhibin alpha subunit
Gene Symbols INHA
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Inhibin alpha. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16322, 3623
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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