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Invitrogen™ INHA Polyclonal Antibody
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Catalog No. PIPA5119909
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100 μL
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PIPA5119909 100 μL
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Catalog No. PIPA5119909 Supplier Invitrogen™ Supplier No. PA5119909
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Description

Rabbit Polyclonal Antibody

Positive Control: K562 cell lysate, Hela cell lysate, rat testis tissue lysates, MCF-7, Hela, SiHa. Subcellular Location: Secreted.

The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
TRUSTED_SUSTAINABILITY

Specifications

Antigen INHA
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene INHA
Gene Accession No. P05111, P17490
Gene Alias A inhibin subunit; A-inhibin subunit; AW555078; IHA; Inha; inhibin; inhibin alpha; inhibin alpha chain; inhibin alpha subunit
Gene Symbols INHA
Host Species Rabbit
Immunogen Synthetic peptide within human INHA aa 100-200.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24504, 3623
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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